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VOL. 1, ISSUE 1 (2025)
Evaluating the Relationship of Mean Platelet Volume and HbA1c with Diabetic Retinopathy in Adults with Diabetes
Authors
Dr. Nithin K
Abstract
Diabetic retinopathy is a common microvascular
complication of diabetes and a leading cause of vision impairment in adults.
Early identification of biomarkers associated with its development and
progression is critical for improving patient outcomes. Blood samples were
collected to measure MPV and HbA1c levels using standardized laboratory
techniques. The results indicated that adults with diabetic retinopathy had
significantly higher mean MPV (11.2 ± 0.9 fL) and HbA1c (8.4% ± 1.1%) compared
to those without retinopathy (MPV: 10.2 ± 0.7 fL; HbA1c: 7.1% ± 0.8%; p <
0.001). Further stratification revealed a positive correlation between both MPV
and HbA1c levels with the severity of retinopathy, with proliferative stages
demonstrating the highest values. Multivariate regression analysis confirmed
that elevated MPV and poor glycemic control were independent predictors of
retinopathy, even after adjusting for age, diabetes duration, and blood
pressure. These findings suggest that routine monitoring of MPV and HbA1c may
provide valuable clinical insight into the risk and progression of diabetic
retinopathy. Integrating these hematologic and glycemic markers into regular
diabetic care could facilitate earlier intervention and reduce the burden of
vision loss in affected individuals.
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Pages:1-4
How to cite this article:
Dr. Nithin K "Evaluating the Relationship of Mean Platelet Volume and HbA1c with Diabetic Retinopathy in Adults with Diabetes". World Journal of Diabetes, Vol 1, Issue 1, 2025, Pages 1-4
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